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This technique depends on the slow release and passive diffusion of the drug molecule, perhaps augmented by the liposomal formulation and its interaction with skin lipids [32]
New GS paralogues acquired multiple dorsal gland promoter elements, altered spatial expression to the secretory dorsal gland, altered temporal expression to primarily parasitic stages, and gained a signal peptide for secretion
On day 14, the mice were euthanized, and a histological analysis of the major organs was performed using H&E staining
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Phase 3 represents the early secretory phase and is marked by upregulation of MTF1 , a transcriptional activator of the metallothionein I promoter regulating the expression of multiple metallothionein I genes ( MT1E, MT1F, MT1G, MT1X ) [11, 22] (Fig
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