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Athletes may be using these substances in the belief that they will give them an edge, although how common these illicit practices are is unknown, as they are shrouded in secrecy

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Upon receptor-mediated endocytosis and lysosomal degradation, these nanoparticles release free PROTAC, leading to cytoplasmic PD-L1 degradation via the UPS and offering a new strategy for cancer immunotherapy [198]